Levest® – A lower cost,1–3 bioequivalent alternative to Microgynon® 304,5
- Levest® is a monophasic combined oral contraceptive (COC) pill which contains 150 mcg levonorgestrel and 30 mcg ethinylestradiol3
- Levest® contains the same active ingredients and has demonstrated bioequivalence to Microgynon® 30, therefore, following appropriate patient assessment and review, it may be prescribed in place of Microgynon® 303–6
- Each pack of Levest® contains 3 x blister strips of 21 tablets for 3 cycles of contraceptive cover7
References
- UK drug tariff (Accessed April 2024)
- NHS dm+d. Actual Medicinal Product (AMP) Microgynon 30 tablets (Bayer PLC). Available at: https://dmd-browser.nhsbsa.nhs.uk/amp/view/5014 (accessed January 2024);
- NHS dm+d. Actual Medicinal Product (AMP) Levest 150/30 tablets (Actavis UK Ltd). Available at: https://dmd-browser.nhsbsa.nhs.uk/amp/view/59244 (accessed January 2024);
- MHRA. UK PAR Levonorgestrel/Ethinylestradiol 150/30 microgram coated tablets. Available at: https://mhraproductsproduction.blob.core.windows.net/docs/ca50b58c7d0d8c6fe9d2d53ec38d2d1f17ff7e1f (accessed January 2024);
- MHRA. UK PAR Femicept 150/30 coated tablets, Levest 150/30 coated tablets (levonorgestrel, ethinylestradiol). Available at: https://www.geneesmiddeleninformatiebank.nl/Pars/h102777.pdf (accessed January 2024);
- Bayer PLC. Microgynon 30 tablets. Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/1130/ (accessed January 2024);
- NHS dm+d. Actual Medicinal Product Pack (AMPP) Levest 150/30 tablets (Actavis UK Ltd). 63 tablet 3 x 21 tablets. Available at: https://dmd-browser.nhsbsa.nhs.uk/ampp/view/72706 (accessed January 2024).
Microgynon® 30 chosen as a comparator as it is the license reference product for Levest®.4,5